Mode d'action et effets de la caféine

Mode d'action


- Blocage des récepteurs à adénosine



La caféine étant un antagoniste de l'adénosine, on remarque les similitudes existantes entre ces deux substances, au niveau des atomes d'azote, ainsi, la caféine peut se placer dans les récepteurs à adénosine.









- Inhibition de la phosphodiestérase (ne catabolise plus l'AMPc)



- libération de catécholamines (substance produite par les neurones permettant la transmission de l'influx nerveux)
- mobilisation du Ca2+ intracellulaire






Première approche des effets potentiels :

Effets sur le système nerveux central
- A forte dose, la caféine est anxiogène et peut provoquer des tremblements

Effets sur le système cardio-vasculaire
- Cardiotonique, à forte dose provoque des palpitations

Effets sur le système rénal
- Effet diurétique (augmentation de quantité d'urine)

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